Electrochemical Behavior of a Copper Tungstate-Fabricated Disposable Strip for the Rapid and Real-Time Detection of Uric Acid

Balasubramanian Sriram; Shanavas Shajahan; Yung−Fu Hsu; Sea Fue Wang; Mohammad Abu Haija

doi:10.1021/acsanm.2c02645

Electrochemical Behavior of a Copper Tungstate-Fabricated Disposable Strip for the Rapid and Real-Time Detection of Uric Acid

Balasubramanian Sriram, Shanavas Shajahan, Yung−Fu Hsu, Sea Fue Wang, Mohammad Abu Haija

Chemistry

National Taipei University of Technology

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Researchers are now aiming to develop multifunctional materials that are nontoxic, minimal in cost, and simple to produce and have superior efficiency for large-scale electrochemical sensor applications. Uric acid (UA) is a biomarker correlated with gout and kidney stones that has an adverse effect on the human body. Here, UA was measured using differential pulse voltammetry (DPV) and amperometric (i-t) techniques with a superactive Wolframite structure of CuWO₄. CuWO₄ was characterized using a variety of microscopic and spectroscopic methods. The data collected indicated that the electrode modified with CuWO₄ provides a superior electrochemical oxidation peak current compared with the bare electrode. CuWO₄ exhibits wide linear ranges, with a lower limit of detection obtained from DPV and i-t techniques. Furthermore, the CuWO₄-modified sensor has been used to determine the concentration of UA in urine and bovine serum albumin samples. Moreover, the CuWO₄-modified sensor has great stability and reproducibility.

Original language	British English
Pages (from-to)	1-9
Number of pages	9
Journal	ACS Applied Nano Materials
Volume	6
Issue number	1
DOIs	https://doi.org/10.1021/acsanm.2c02645
State	Published - 13 Jan 2023

Keywords

CuWO
electrochemical approach
inorganic nanomaterials
real-world samples
uric acid

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title = "Electrochemical Behavior of a Copper Tungstate-Fabricated Disposable Strip for the Rapid and Real-Time Detection of Uric Acid",

abstract = "Researchers are now aiming to develop multifunctional materials that are nontoxic, minimal in cost, and simple to produce and have superior efficiency for large-scale electrochemical sensor applications. Uric acid (UA) is a biomarker correlated with gout and kidney stones that has an adverse effect on the human body. Here, UA was measured using differential pulse voltammetry (DPV) and amperometric (i-t) techniques with a superactive Wolframite structure of CuWO4. CuWO4 was characterized using a variety of microscopic and spectroscopic methods. The data collected indicated that the electrode modified with CuWO4 provides a superior electrochemical oxidation peak current compared with the bare electrode. CuWO4 exhibits wide linear ranges, with a lower limit of detection obtained from DPV and i-t techniques. Furthermore, the CuWO4-modified sensor has been used to determine the concentration of UA in urine and bovine serum albumin samples. Moreover, the CuWO4-modified sensor has great stability and reproducibility.",

keywords = "CuWO, electrochemical approach, inorganic nanomaterials, real-world samples, uric acid",

author = "Balasubramanian Sriram and Shanavas Shajahan and Yung−Fu Hsu and Wang, {Sea Fue} and Haija, {Mohammad Abu}",

note = "Funding Information: This work was financially supported by the Ministry of Science and Technology (MOST-108-2221-E-027-063) and NTUT and Tamil Nadu State Council for Science and Technology. S.S. and M.A.H. are grateful to Khalifa University of Science and Technology for supporting this study through Grant CIRA-2020-085. Publisher Copyright: {\textcopyright} 2022 The Authors. Published by American Chemical Society.",

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AU - Shajahan, Shanavas

AU - Hsu, Yung−Fu

AU - Wang, Sea Fue

AU - Haija, Mohammad Abu

N1 - Funding Information: This work was financially supported by the Ministry of Science and Technology (MOST-108-2221-E-027-063) and NTUT and Tamil Nadu State Council for Science and Technology. S.S. and M.A.H. are grateful to Khalifa University of Science and Technology for supporting this study through Grant CIRA-2020-085. Publisher Copyright: © 2022 The Authors. Published by American Chemical Society.

PY - 2023/1/13

Y1 - 2023/1/13

N2 - Researchers are now aiming to develop multifunctional materials that are nontoxic, minimal in cost, and simple to produce and have superior efficiency for large-scale electrochemical sensor applications. Uric acid (UA) is a biomarker correlated with gout and kidney stones that has an adverse effect on the human body. Here, UA was measured using differential pulse voltammetry (DPV) and amperometric (i-t) techniques with a superactive Wolframite structure of CuWO4. CuWO4 was characterized using a variety of microscopic and spectroscopic methods. The data collected indicated that the electrode modified with CuWO4 provides a superior electrochemical oxidation peak current compared with the bare electrode. CuWO4 exhibits wide linear ranges, with a lower limit of detection obtained from DPV and i-t techniques. Furthermore, the CuWO4-modified sensor has been used to determine the concentration of UA in urine and bovine serum albumin samples. Moreover, the CuWO4-modified sensor has great stability and reproducibility.

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Electrochemical Behavior of a Copper Tungstate-Fabricated Disposable Strip for the Rapid and Real-Time Detection of Uric Acid

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Keywords

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