Electrochemical Behavior of a Copper Tungstate-Fabricated Disposable Strip for the Rapid and Real-Time Detection of Uric Acid

Balasubramanian Sriram, Shanavas Shajahan, Yung−Fu Hsu, Sea Fue Wang, Mohammad Abu Haija

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Researchers are now aiming to develop multifunctional materials that are nontoxic, minimal in cost, and simple to produce and have superior efficiency for large-scale electrochemical sensor applications. Uric acid (UA) is a biomarker correlated with gout and kidney stones that has an adverse effect on the human body. Here, UA was measured using differential pulse voltammetry (DPV) and amperometric (i-t) techniques with a superactive Wolframite structure of CuWO4. CuWO4 was characterized using a variety of microscopic and spectroscopic methods. The data collected indicated that the electrode modified with CuWO4 provides a superior electrochemical oxidation peak current compared with the bare electrode. CuWO4 exhibits wide linear ranges, with a lower limit of detection obtained from DPV and i-t techniques. Furthermore, the CuWO4-modified sensor has been used to determine the concentration of UA in urine and bovine serum albumin samples. Moreover, the CuWO4-modified sensor has great stability and reproducibility.

Original languageBritish English
Pages (from-to)1-9
Number of pages9
JournalACS Applied Nano Materials
Volume6
Issue number1
DOIs
StatePublished - 13 Jan 2023

Keywords

  • CuWO
  • electrochemical approach
  • inorganic nanomaterials
  • real-world samples
  • uric acid

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