Efficacy of Frequency Domain Parameters applied onto ultra-short ECG Recordings in the Diagnosis of Definite Cardiac Autonomic Neuropathy - Comparing Lomb-Scargle-Periodogram and Fast-Fourier-Transform

Dominik Wehler, Herbert F. Jelinek, Niels Wessel, Jan F. Kramer, Thomas Penzel

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Cardiac autonomic neuropathy (CAN) is often, but not always, linked to diabetes and should therefore be part of a general health review. Analysis of heart rate variability (HRV), the beat-to-beat alterations in heart rate, is a potential screening tool in general practice, but optimal recording lengths and diagnostic parameters need to be established. We calculated the low frequency (LF) and high frequency (HF) frequency domain parameters for 11 patients with definite CAN (dCAN) and 76 controls from ultra-short ECGs of 10 to 300 seconds in length and their ability to distinguish dCAN from controls was assessed by estimation of an area under the receiver operating characteristic curve (AUC). Fast-Fourier-Transform (FFT) and Lomb-Scargle-Periodogram (LSP) have been used separately to allow for a comparison of methods. LF and HF allowed for good overall separation of groups from 300-second-recordings, which had the highest accuracy and has been the traditional recommended length for frequency domain analysis, with LF yielding good results down to 60 secs, The differences between values obtained through FFT and LSP were clinically negligible for all window sizes.

Original languageBritish English
Title of host publication2020 11th Conference of the European Study Group on Cardiovascular Oscillations
Subtitle of host publicationComputation and Modelling in Physiology: New Challenges and Opportunities, ESGCO 2020
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781728157511
DOIs
StatePublished - Jul 2020
Event11th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2020 - Virtual, Online, Italy
Duration: 15 Jul 2020 → …

Publication series

Name2020 11th Conference of the European Study Group on Cardiovascular Oscillations: Computation and Modelling in Physiology: New Challenges and Opportunities, ESGCO 2020

Conference

Conference11th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2020
Country/TerritoryItaly
CityVirtual, Online
Period15/07/20 → …

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