TY - JOUR
T1 - Discrimination between calcium hydroxyapatite and calcium oxalate using multienergy spectral photon-counting CT
AU - Kirkbride, Tracy E.
AU - Raja, Aamir Y.
AU - Müller, Kristin
AU - Bateman, Christopher J.
AU - Becce, Fabio
AU - Anderson, Nigel G.
N1 - Funding Information:
Supported in part by project grant PROJ-13860-NMTS-UOC from the New Zealand Foundation for Research, Science, and Technology.
Publisher Copyright:
© 2017 American Roentgen Ray Society.
PY - 2017/11
Y1 - 2017/11
N2 - OBJECTIVE. We aimed to determine whether multienergy spectral photon-counting CT could distinguish between clinically relevant calcium crystals at clinical x-ray energy ranges. Energy thresholds of 15, 22, 29, and 36 keV and tube voltages of 50, 80, and 110 kVp were selected. Images were analyzed to assess differences in linear attenuation coeffcients between various concentrations of calcium hydroxyapatite (54.3, 211.7, 808.5, and 1169.3 mg/cm3) and calcium oxalate (2000 mg/cm3). CONCLUSION. The two lower concentrations of hydroxyapatite were distinguishable from oxalate at all energy thresholds and tube voltages, whereas discrimination at higher concentrations depended primarily on the energy thresholds used. Multienergy spectral photoncounting CT shows promise for distinguishing these calcium crystals.
AB - OBJECTIVE. We aimed to determine whether multienergy spectral photon-counting CT could distinguish between clinically relevant calcium crystals at clinical x-ray energy ranges. Energy thresholds of 15, 22, 29, and 36 keV and tube voltages of 50, 80, and 110 kVp were selected. Images were analyzed to assess differences in linear attenuation coeffcients between various concentrations of calcium hydroxyapatite (54.3, 211.7, 808.5, and 1169.3 mg/cm3) and calcium oxalate (2000 mg/cm3). CONCLUSION. The two lower concentrations of hydroxyapatite were distinguishable from oxalate at all energy thresholds and tube voltages, whereas discrimination at higher concentrations depended primarily on the energy thresholds used. Multienergy spectral photoncounting CT shows promise for distinguishing these calcium crystals.
KW - Calcium hydroxyapatite
KW - Calcium oxalate
KW - Ectopic calcifcations
KW - Linear attenuation coeffcients
KW - Multienergy spectral photon-counting CT
UR - http://www.scopus.com/inward/record.url?scp=85032707762&partnerID=8YFLogxK
U2 - 10.2214/AJR.17.18394
DO - 10.2214/AJR.17.18394
M3 - Article
C2 - 28834448
AN - SCOPUS:85032707762
SN - 0361-803X
VL - 209
SP - 1088
EP - 1092
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
IS - 5
ER -