TY - JOUR
T1 - Differential expression of the estrogen receptor-related receptor γ in the mouse brain
AU - Lorke, Dietrich E.
AU - Süsens, Ute
AU - Borgmeyer, Uwe
AU - Hermans-Borgmeyer, Irm
PY - 2000/5/5
Y1 - 2000/5/5
N2 - To elucidate estrogen functions, the expression of the estrogen receptor-related receptor ERRγ, a novel orphan nuclear receptor regulating transcription via estrogen responsive elements, has been localized by in situ hybridization in adult murine brain. ERRγ transcripts were abundantly present in the isocortex, the olfactory system, cranial nerve nuclei and major parts of the coordination centers, e.g. reticular formation and major parts of the extrapyramidal motor systems. In addition, ERRγ expression was detected in trigeminal ganglion neurons. ERRγ distribution was clearly distinguished from that described for ERRα, for ERRβ, and for estrogen receptors (ER) pointing at functional differences between ERRγ and these receptors. (C) 2000 Elsevier Science B.V.
AB - To elucidate estrogen functions, the expression of the estrogen receptor-related receptor ERRγ, a novel orphan nuclear receptor regulating transcription via estrogen responsive elements, has been localized by in situ hybridization in adult murine brain. ERRγ transcripts were abundantly present in the isocortex, the olfactory system, cranial nerve nuclei and major parts of the coordination centers, e.g. reticular formation and major parts of the extrapyramidal motor systems. In addition, ERRγ expression was detected in trigeminal ganglion neurons. ERRγ distribution was clearly distinguished from that described for ERRα, for ERRβ, and for estrogen receptors (ER) pointing at functional differences between ERRγ and these receptors. (C) 2000 Elsevier Science B.V.
KW - Expression
KW - In situ hybridization
KW - Orphan nuclear receptor
UR - http://www.scopus.com/inward/record.url?scp=0343776953&partnerID=8YFLogxK
U2 - 10.1016/S0169-328X(00)00063-2
DO - 10.1016/S0169-328X(00)00063-2
M3 - Article
C2 - 10837923
AN - SCOPUS:0343776953
SN - 0169-328X
VL - 77
SP - 277
EP - 280
JO - Molecular Brain Research
JF - Molecular Brain Research
IS - 2
ER -