TY - JOUR
T1 - Development of polyhydroxyalkanoates production from waste feedstocks and applications
AU - Pakalapati, Harshini
AU - Chang, Chih Kai
AU - Show, Pau Loke
AU - Arumugasamy, Senthil Kumar
AU - Lan, John Chi Wei
N1 - Funding Information:
John Chi-Wei Lan would like to express highly appreciation to the Society for Biotechnology, Japan, which awarded him the Young Asian Biotechnologist Prize in 2017. The authors appreciate financial support of the Fundamental Research Grant Scheme (Malaysia, FRGS/1/2015/SG05/UNIM/03/1), the Ministry of Science and Technology, (Taiwan, MOST 106-2621-M-155-001), and the Prototype Research Grant Scheme (PRGS/2/2015/SG05/UNIM/03/1).
Funding Information:
John Chi-Wei Lan would like to express highly appreciation to the Society for Biotechnology, Japan, which awarded him the Young Asian Biotechnologist Prize in 2017. The authors appreciate financial support of the Fundamental Research Grant Scheme (Malaysia, FRGS/1/2015/SG05/UNIM/03/1 ), the Ministry of Science and Technology , (Taiwan, MOST 106-2621-M-155-001 ), and the Prototype Research Grant Scheme ( PRGS/2/2015/SG05/UNIM/03/1 ).
Publisher Copyright:
© 2018 The Society for Biotechnology, Japan
PY - 2018/9
Y1 - 2018/9
N2 - Polyhydroxyalkanoates (PHA) are naturally occurring biopolymers, obtained from microorganisms. Properties like biodegradability and biocompatibility make PHA a part of today's commercial polymer industry. However, the production cost of PHA has been a great barrier to extend its application to large scale production. Substrates and usage of pure cultures constitute the main reason for its high production cost. On the other hand, rapid industrialization i.e., industrial sectors such as sugar, pulp and paper, fruit and food processing, dairies, slaughterhouses, and poultries, has resulted in the generation of the huge quantity of wastes. Consequently, becoming large source of environmental pollution and health hazard. This review emphasizes on the usage of various waste feedstocks obtained from industrial and agricultural industries as an alternate substrate for PHA production. As these waste materials are rich in organic material and also microbes, they can be the good starting material for PHA production. Additionally, advantages and economic importance of mixed cultures and also PHA applications are discussed. Future prospects and challenges in PHA production from waste feedstocks are also highlighted.
AB - Polyhydroxyalkanoates (PHA) are naturally occurring biopolymers, obtained from microorganisms. Properties like biodegradability and biocompatibility make PHA a part of today's commercial polymer industry. However, the production cost of PHA has been a great barrier to extend its application to large scale production. Substrates and usage of pure cultures constitute the main reason for its high production cost. On the other hand, rapid industrialization i.e., industrial sectors such as sugar, pulp and paper, fruit and food processing, dairies, slaughterhouses, and poultries, has resulted in the generation of the huge quantity of wastes. Consequently, becoming large source of environmental pollution and health hazard. This review emphasizes on the usage of various waste feedstocks obtained from industrial and agricultural industries as an alternate substrate for PHA production. As these waste materials are rich in organic material and also microbes, they can be the good starting material for PHA production. Additionally, advantages and economic importance of mixed cultures and also PHA applications are discussed. Future prospects and challenges in PHA production from waste feedstocks are also highlighted.
KW - Agricultural waste
KW - Industrial waste
KW - Medical applications
KW - Mixed cultures
KW - Polyhydroxyalkanoates
UR - http://www.scopus.com/inward/record.url?scp=85047300160&partnerID=8YFLogxK
U2 - 10.1016/j.jbiosc.2018.03.016
DO - 10.1016/j.jbiosc.2018.03.016
M3 - Review article
C2 - 29803402
AN - SCOPUS:85047300160
SN - 1389-1723
VL - 126
SP - 282
EP - 292
JO - Journal of Bioscience and Bioengineering
JF - Journal of Bioscience and Bioengineering
IS - 3
ER -
