Degradation of biodegradable implants: The influence of microstructure and composition of Mg-Zn-Ca alloys

V. Roche; G. Y. Koga; T. B. Matias; C. S. Kiminami; C. Bolfarini; W. J. Botta; R. P. Nogueira; A. M. Jorge Junior

doi:10.1016/j.jallcom.2018.09.346

Degradation of biodegradable implants: The influence of microstructure and composition of Mg-Zn-Ca alloys

V. Roche, G. Y. Koga, T. B. Matias, C. S. Kiminami, C. Bolfarini, W. J. Botta, R. P. Nogueira, A. M. Jorge Junior

Chemical and Petroleum Engineering

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

This work reports on the degradation of two (Zn-poor and Zn-rich) Mg-Zn-Ca crystalline alloys produced by mold casting yielding different kinds of microstructures with several scales. The dependence of corrosion properties and hydrogen evolution with alloy compositions, sizes and kinds of microstructure was exhaustively analyzed. The results were compared with amorphous alloys of same compositions. Zn-rich composition with average grain sizes of less than 500 nm presented marginal and an acceptable level of hydrogen, which was lower than for larger grains or Zn-poor composition. This behavior was explained by the reduction of the intrinsic metallic surface reactivity and the higher stability of the oxide film, which reduce the corrosion rate and, consequently, the hydrogen evolution. Mg-Zn-Ca crystalline alloys with Zn-alloying threshold and homogeneous grain size (<500 nm) appear hence to be of great potential for use in biodegradable implants.

Original language	British English
Pages (from-to)	168-181
Number of pages	14
Journal	Journal of Alloys and Compounds
Volume	774
DOIs	https://doi.org/10.1016/j.jallcom.2018.09.346
State	Published - 5 Feb 2019

Keywords

Amorphous materials
Biodegradation
Biomaterials
Degradation scalability
Implants
Mg-Zn-Ca alloys
Ultrafine grains

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jallcom.2018.09.346

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@article{9ae1d80fd99d4e568e50f3e29cf00ee5,

title = "Degradation of biodegradable implants: The influence of microstructure and composition of Mg-Zn-Ca alloys",

abstract = "This work reports on the degradation of two (Zn-poor and Zn-rich) Mg-Zn-Ca crystalline alloys produced by mold casting yielding different kinds of microstructures with several scales. The dependence of corrosion properties and hydrogen evolution with alloy compositions, sizes and kinds of microstructure was exhaustively analyzed. The results were compared with amorphous alloys of same compositions. Zn-rich composition with average grain sizes of less than 500 nm presented marginal and an acceptable level of hydrogen, which was lower than for larger grains or Zn-poor composition. This behavior was explained by the reduction of the intrinsic metallic surface reactivity and the higher stability of the oxide film, which reduce the corrosion rate and, consequently, the hydrogen evolution. Mg-Zn-Ca crystalline alloys with Zn-alloying threshold and homogeneous grain size (<500 nm) appear hence to be of great potential for use in biodegradable implants.",

keywords = "Amorphous materials, Biodegradation, Biomaterials, Degradation scalability, Implants, Mg-Zn-Ca alloys, Ultrafine grains",

author = "V. Roche and Koga, \{G. Y.\} and Matias, \{T. B.\} and Kiminami, \{C. S.\} and C. Bolfarini and Botta, \{W. J.\} and Nogueira, \{R. P.\} and \{Jorge Junior\}, \{A. M.\}",

note = "Funding Information: This work was funded by FAPESP under the grant number FAPESP Tematic \# 2013/05987-8 . T.B.M acknowledges CNPq ( \# 200635/2014-0 (PDE)) -Science without Border Program and A.M.J.J. acknowledges FAPESP fellowship through grant number 2012/13179-6 . The authors also would like to thank Eng. Isadora Vi{\c c}osa and MSc. Gabriela P. Danez for their support in electrochemical tests and in producing alloys. Publisher Copyright: {\textcopyright} 2018 Elsevier B.V.",

year = "2019",

month = feb,

day = "5",

doi = "10.1016/j.jallcom.2018.09.346",

language = "British English",

volume = "774",

pages = "168--181",

journal = "Journal of Alloys and Compounds",

issn = "0925-8388",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - Degradation of biodegradable implants

T2 - The influence of microstructure and composition of Mg-Zn-Ca alloys

AU - Roche, V.

AU - Koga, G. Y.

AU - Matias, T. B.

AU - Kiminami, C. S.

AU - Bolfarini, C.

AU - Botta, W. J.

AU - Nogueira, R. P.

AU - Jorge Junior, A. M.

N1 - Funding Information: This work was funded by FAPESP under the grant number FAPESP Tematic # 2013/05987-8 . T.B.M acknowledges CNPq ( # 200635/2014-0 (PDE)) -Science without Border Program and A.M.J.J. acknowledges FAPESP fellowship through grant number 2012/13179-6 . The authors also would like to thank Eng. Isadora Viçosa and MSc. Gabriela P. Danez for their support in electrochemical tests and in producing alloys. Publisher Copyright: © 2018 Elsevier B.V.

PY - 2019/2/5

Y1 - 2019/2/5

N2 - This work reports on the degradation of two (Zn-poor and Zn-rich) Mg-Zn-Ca crystalline alloys produced by mold casting yielding different kinds of microstructures with several scales. The dependence of corrosion properties and hydrogen evolution with alloy compositions, sizes and kinds of microstructure was exhaustively analyzed. The results were compared with amorphous alloys of same compositions. Zn-rich composition with average grain sizes of less than 500 nm presented marginal and an acceptable level of hydrogen, which was lower than for larger grains or Zn-poor composition. This behavior was explained by the reduction of the intrinsic metallic surface reactivity and the higher stability of the oxide film, which reduce the corrosion rate and, consequently, the hydrogen evolution. Mg-Zn-Ca crystalline alloys with Zn-alloying threshold and homogeneous grain size (<500 nm) appear hence to be of great potential for use in biodegradable implants.

AB - This work reports on the degradation of two (Zn-poor and Zn-rich) Mg-Zn-Ca crystalline alloys produced by mold casting yielding different kinds of microstructures with several scales. The dependence of corrosion properties and hydrogen evolution with alloy compositions, sizes and kinds of microstructure was exhaustively analyzed. The results were compared with amorphous alloys of same compositions. Zn-rich composition with average grain sizes of less than 500 nm presented marginal and an acceptable level of hydrogen, which was lower than for larger grains or Zn-poor composition. This behavior was explained by the reduction of the intrinsic metallic surface reactivity and the higher stability of the oxide film, which reduce the corrosion rate and, consequently, the hydrogen evolution. Mg-Zn-Ca crystalline alloys with Zn-alloying threshold and homogeneous grain size (<500 nm) appear hence to be of great potential for use in biodegradable implants.

KW - Amorphous materials

KW - Biodegradation

KW - Biomaterials

KW - Degradation scalability

KW - Implants

KW - Mg-Zn-Ca alloys

KW - Ultrafine grains

UR - https://www.scopus.com/pages/publications/85054158864

U2 - 10.1016/j.jallcom.2018.09.346

DO - 10.1016/j.jallcom.2018.09.346

M3 - Article

AN - SCOPUS:85054158864

SN - 0925-8388

VL - 774

SP - 168

EP - 181

JO - Journal of Alloys and Compounds

JF - Journal of Alloys and Compounds

ER -

Degradation of biodegradable implants: The influence of microstructure and composition of Mg-Zn-Ca alloys

Abstract

Keywords

UN SDGs

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