TY - JOUR
T1 - DeepFoG
T2 - An IMU-Based Detection of Freezing of Gait Episodes in Parkinson’s Disease Patients via Deep Learning
AU - Bikias, Thomas
AU - Iakovakis, Dimitrios
AU - Hadjidimitriou, Stelios
AU - Charisis, Vasileios
AU - Hadjileontiadis, Leontios J.
N1 - Funding Information:
The research leading to these results has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 690494 - i-PROGNOSIS: Intelligent Parkinson early detection guiding novel supportive interventions.
Publisher Copyright:
© Copyright © 2021 Bikias, Iakovakis, Hadjidimitriou, Charisis and Hadjileontiadis.
PY - 2021/5/7
Y1 - 2021/5/7
N2 - Freezing of Gait (FoG) is a movement disorder that mostly appears in the late stages of Parkinson’s Disease (PD). It causes incapability of walking, despite the PD patient’s intention, resulting in loss of coordination that increases the risk of falls and injuries and severely affects the PD patient’s quality of life. Stress, emotional stimulus, and multitasking have been encountered to be associated with the appearance of FoG episodes, while the patient’s functionality and self-confidence are constantly deteriorating. This study suggests a non-invasive method for detecting FoG episodes, by analyzing inertial measurement unit (IMU) data. Specifically, accelerometer and gyroscope data from 11 PD subjects, as captured from a single wrist-worn IMU sensor during continuous walking, are processed via Deep Learning for window-based detection of the FoG events. The proposed approach, namely DeepFoG, was evaluated in a Leave-One-Subject-Out (LOSO) cross-validation (CV) and 10-fold CV fashion schemes against its ability to correctly estimate the existence or not of a FoG episode at each data window. Experimental results have shown that DeepFoG performs satisfactorily, as it achieves 83%/88% and 86%/90% sensitivity/specificity, for LOSO CV and 10-fold CV schemes, respectively. The promising performance of the proposed DeepFoG reveals the potentiality of single-arm IMU-based real-time FoG detection that could guide effective interventions via stimuli, such as rhythmic auditory stimulation (RAS) and hand vibration. In this way, DeepFoG may scaffold the elimination of risk of falls in PD patients, sustaining their quality of life in everyday living activities.
AB - Freezing of Gait (FoG) is a movement disorder that mostly appears in the late stages of Parkinson’s Disease (PD). It causes incapability of walking, despite the PD patient’s intention, resulting in loss of coordination that increases the risk of falls and injuries and severely affects the PD patient’s quality of life. Stress, emotional stimulus, and multitasking have been encountered to be associated with the appearance of FoG episodes, while the patient’s functionality and self-confidence are constantly deteriorating. This study suggests a non-invasive method for detecting FoG episodes, by analyzing inertial measurement unit (IMU) data. Specifically, accelerometer and gyroscope data from 11 PD subjects, as captured from a single wrist-worn IMU sensor during continuous walking, are processed via Deep Learning for window-based detection of the FoG events. The proposed approach, namely DeepFoG, was evaluated in a Leave-One-Subject-Out (LOSO) cross-validation (CV) and 10-fold CV fashion schemes against its ability to correctly estimate the existence or not of a FoG episode at each data window. Experimental results have shown that DeepFoG performs satisfactorily, as it achieves 83%/88% and 86%/90% sensitivity/specificity, for LOSO CV and 10-fold CV schemes, respectively. The promising performance of the proposed DeepFoG reveals the potentiality of single-arm IMU-based real-time FoG detection that could guide effective interventions via stimuli, such as rhythmic auditory stimulation (RAS) and hand vibration. In this way, DeepFoG may scaffold the elimination of risk of falls in PD patients, sustaining their quality of life in everyday living activities.
KW - deep learning
KW - deepFoG
KW - freezing of gait
KW - Parkinson's disease
KW - rhythmic auditory stimulation
KW - smartwatch
UR - http://www.scopus.com/inward/record.url?scp=85107428508&partnerID=8YFLogxK
U2 - 10.3389/frobt.2021.537384
DO - 10.3389/frobt.2021.537384
M3 - Article
AN - SCOPUS:85107428508
SN - 2296-9144
VL - 8
JO - Frontiers in Robotics and AI
JF - Frontiers in Robotics and AI
M1 - 537384
ER -