Curcuma longa extract as a histological dye for collagen fibres and red blood cells

O. G. Avwioro, S. K. Onwuka, J. O. Moody, J. M. Agbedahunsi, T. Oduola, O. E. Ekpo, A. A. Oladele

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23 Scopus citations


Crude ethanolic extract and column chromatographic fractions of the Allepey cultivar of Curcuma longa Roxb, commonly called turmeric (tumeric) in commerce, were used as a stain for tissue sections. Staining was carried out under basic, acidic and neutral media conditions. Inorganic and organic dissolution solvents were used. The stain was used as a counterstain after alum and iron haematoxylins. C. longa stained collagen fibres, cytoplasm, red blood cells and muscle cells yellow. It also stained in a fashion similar to eosin, except for its intense yellow colour. Preliminary phytochemical evaluation of the active column fraction revealed that it contained flavonoids, free anthraquinone and deoxy sugar. A cheap, natural dye can thus be obtained from C. longa.

Original languageBritish English
Pages (from-to)600-603
Number of pages4
JournalJournal of Anatomy
Issue number5
StatePublished - May 2007


  • Curcuma longa
  • Flavonoid and stain
  • Rhizome
  • Turmeric (tumeric)
  • Zingiberaceae


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