TY - JOUR
T1 - Comprehensive Review on the Synthesis, Properties and Applications of Nanocomposite Contact Lenses
AU - Sakr, Abdelrahman
AU - Kamal, Abdallah
AU - Jacob, Liya
AU - Homsi, Rami
AU - Butt, Haider
N1 - Publisher Copyright:
© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.
PY - 2025
Y1 - 2025
N2 - Nanocomposite contact lenses (NCLs) have emerged as a promising advancement in the field of ophthalmic materials, combining the advantages of traditional contact lenses with the unique properties offered by nanomaterials. This review presents a comprehensive overview of the recent developments and applications of NCLs. The synthesis methods and characterization techniques for nanocomposite materials are discussed, along with a focus on the incorporation of various nanoparticles, such as metallic, polymeric, and inorganic nanoparticles, into contact lens matrices. The impact of these nanoparticles on the physical, mechanical, and optical properties of the lenses is highlighted. The review addresses the applications of NCLs in areas such as drug delivery, vision correction, biosensing, and antimicrobial activity. The controlled release capabilities of nanocomposite lenses for therapeutic agents, the enhanced optical performance achieved through nanoparticle incorporation, the potential for biosensing and diagnostic applications, and the antimicrobial properties of NCLs are examined in detail. Furthermore, the challenges and future prospects in the field of NCLs are discussed, emphasizing the need for further research in areas such as biocompatibility, long-term stability, and clinical translation. Overall, NCLs hold tremendous potential for advancing ophthalmic technologies and providing innovative solutions for improved ocular health and vision care.
AB - Nanocomposite contact lenses (NCLs) have emerged as a promising advancement in the field of ophthalmic materials, combining the advantages of traditional contact lenses with the unique properties offered by nanomaterials. This review presents a comprehensive overview of the recent developments and applications of NCLs. The synthesis methods and characterization techniques for nanocomposite materials are discussed, along with a focus on the incorporation of various nanoparticles, such as metallic, polymeric, and inorganic nanoparticles, into contact lens matrices. The impact of these nanoparticles on the physical, mechanical, and optical properties of the lenses is highlighted. The review addresses the applications of NCLs in areas such as drug delivery, vision correction, biosensing, and antimicrobial activity. The controlled release capabilities of nanocomposite lenses for therapeutic agents, the enhanced optical performance achieved through nanoparticle incorporation, the potential for biosensing and diagnostic applications, and the antimicrobial properties of NCLs are examined in detail. Furthermore, the challenges and future prospects in the field of NCLs are discussed, emphasizing the need for further research in areas such as biocompatibility, long-term stability, and clinical translation. Overall, NCLs hold tremendous potential for advancing ophthalmic technologies and providing innovative solutions for improved ocular health and vision care.
KW - antibacterial
KW - cytotoxicity
KW - drug delivery
KW - hydrogels
KW - Polymer nanocomposites
KW - sensing
UR - http://www.scopus.com/inward/record.url?scp=85204201603&partnerID=8YFLogxK
U2 - 10.1080/15583724.2024.2400961
DO - 10.1080/15583724.2024.2400961
M3 - Review article
AN - SCOPUS:85204201603
SN - 1558-3724
VL - 65
SP - 1
EP - 46
JO - Polymer Reviews
JF - Polymer Reviews
IS - 1
ER -