@article{e5fa8e9d54be452f954fb37a15923d03,
title = "Changes in IGF-1 receptors in the hippocampus of adult rats after long- term adrenalectomy: Receptor autoradiography and in situ hybridization histochemistry",
abstract = "Alteration of insulin-like growth factor-1 (IGF-1) receptor and its mRNA after long-term adrenalectomy (ADX) was studied in the hippocampus by in vitro receptor autoradiography and in situ hybridization histochemistry, respectively. Significantly, decreased levels of IGF-1 receptor and its mRNA was noted in the dentate and CA1-CA4 regions of the hippocampus of the ADX animals, suggesting that the level and expression of IGF-1 receptors in the hippocampus is influenced by adrenal hormones.",
keywords = "Apoptosis, Corticosteroid, Growth factor, Neurodegeneration",
author = "A. Islam and C. Ayer-Lelievre and C. Heigensk{\"o}ld and N. Bogdanovic and B. Winblad and A. Adem",
note = "Funding Information: This study was supported by grants Loo och Hans Ostermans Fund, Swedish Society for Medical Research, Stiftelsen Sigurd och Elsa Goljes Minne, KI fonder, Greta Lindenau Hansells Minnesfond and Gamla Tj{\"a}narinnor Foundation. -IGF-1 was donated by Prof. V. Sara. Technical assistance of Ingvild Halbig and Dr. Adlan ElHassan is gratefully acknowledged.",
year = "1998",
month = jun,
day = "29",
doi = "10.1016/S0006-8993(98)00389-8",
language = "British English",
volume = "797",
pages = "342--346",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier B.V.",
number = "2",
}