Camel whey protein with enhanced antioxidative and antimicrobial properties upon simulated gastro-intestinal digestion

Hina Kamal, Sabika Jafar, Priti Mudgil, Marwa Hamdi, Mohammed Akli Ayoub, Sajid Maqsood

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Background: Whey proteins and their peptide derivatives have attracted a great attention of researchers in the pharmaceutical and nutritional fields, due to their numerous bio-functionalities. Aim: In the present research study, enzymatic protein hydrolysates (CWPHs) from camel whey proteins (CWPs) were produced and investigated for their antioxidant and antimicrobial potentials. Methods: Herein, Pepsin (gastric), and Trypsin and Chymotrypsin (pancreatic) enzymes were used to produce CWPHs. The obtained hydrolysates were characterize to ascertain the level of protein degradation and studies on their antimicrobial and antioxidant potential were conducted. Results: Among all CWPHs, a complete degradation of all different protein bands was perceived with Chymotrypsin-derived CWPHs, whereas, light bands of serum albumin and α-lactalbumin were observed with Trypsin and Pepsin-derived CWPHs. After enzymatic degradation, both CWPHs antioxidant and antimicrobial activities were improved. Chymotrypsin-derived CWPHs demonstrated higher DPPH and ABTS radical scavenging activities, anent the increase in proteolysis time. Compared to unhydrolyzed CWPs, higher metal chelating activities were displayed by Trypsin-derived CWPHs. No significant increase in the FRAP activities was noticed after CWPs hydrolysis using Trypsin and Chymotrypsin, while Pepsin-derived CWPHs showed higher reducing power. In terms of antimicrobial activity, significantly higher bacterial growth inhibition rates were exhibited by CWPHs compared to the unhydrolyzed CWP. Conclusion: Overall, CWPHs displayed enhanced antioxidative and antimicrobial properties.

Original languageBritish English
JournalNutrition and Health
StateAccepted/In press - 2022


  • antimicrobial
  • antioxidant
  • Camel whey proteins
  • enzymatic hydrolysis
  • in vitro characterization
  • protein hydrolysates


Dive into the research topics of 'Camel whey protein with enhanced antioxidative and antimicrobial properties upon simulated gastro-intestinal digestion'. Together they form a unique fingerprint.

Cite this