Bioprospecting fungal-derived value-added bioproducts for sustainable pharmaceutical applications

Afifa, Nazim Hussain, Zulqarnain Baqar, Mehvish Mumtaz, Ahmed H. El-Sappah, Pau Loke Show, Hafiz M.N. Iqbal, Sunita Varjani, Muhammad Bilal

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Fungi is a diverse group of microorganisms with over 1.5 million species worldwide. It lives in a variety of environments and develops a variety of survival mechanisms that allow it to manufacture a wide variety of chemicals, i.e., biomolecules. Organic acids, enzymes and secondary metabolites have been shown to be useful in the production of biomolecules. They may be used in a broad range of fields, including pharmaceutical research, agricultural and food biotechnology, commodities biochemicals, agri-foods, chemical engineering, diagnostics, medicines, and medical device development. It also explores fungal macromolecules' health and healing properties, regulates phytohormone synthesis or breakdown in plant roots, improves hormone production, and supports bio-stimulant composition. There are a variety of antimicrobial/antifungal biomolecules in agriculture that may be employed to minimize crop yield-reducing pest and diseases. These biomolecules, which are useful in both the pharmaceutical and agricultural industries, are the focus of this review.

Original languageBritish English
Article number100755
JournalSustainable Chemistry and Pharmacy
Volume29
DOIs
StatePublished - Oct 2022

Keywords

  • Antitumor activity
  • Biological molecules
  • Cardiovascular diseases
  • Cytokinin
  • Diabetes
  • Fungal biomolecules
  • Gibberellins
  • Lipases
  • Xylanases

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