TY - JOUR
T1 - Bionanotechnology and bioMEMS (BNM)
T2 - state-of-the-art applications, opportunities, and challenges
AU - Borenstein, Jeffrey T.
AU - Cummins, Gerard
AU - Dutta, Abhishek
AU - Hamad, Eyad
AU - Hughes, Michael Pycraft
AU - Jiang, Xingyu
AU - Lee, Hyowon Hugh
AU - Lei, Kin Fong
AU - Tang, Xiaowu Shirley
AU - Zheng, Yuanjin
AU - Chen, Jie
N1 - Publisher Copyright:
© 2023 The Royal Society of Chemistry.
PY - 2023/10/20
Y1 - 2023/10/20
N2 - The development of micro- and nanotechnology for biomedical applications has defined the cutting edge of medical technology for over three decades, as advancements in fabrication technology developed originally in the semiconductor industry have been applied to solving ever-more complex problems in medicine and biology. These technologies are ideally suited to interfacing with life sciences, since they are on the scale lengths as cells (microns) and biomacromolecules (nanometers). In this paper, we review the state of the art in bionanotechnology and bioMEMS (collectively BNM), including developments and challenges in the areas of BNM, such as microfluidic organ-on-chip devices, oral drug delivery, emerging technologies for managing infectious diseases, 3D printed microfluidic devices, AC electrokinetics, flexible MEMS devices, implantable microdevices, paper-based microfluidic platforms for cellular analysis, and wearable sensors for point-of-care testing.
AB - The development of micro- and nanotechnology for biomedical applications has defined the cutting edge of medical technology for over three decades, as advancements in fabrication technology developed originally in the semiconductor industry have been applied to solving ever-more complex problems in medicine and biology. These technologies are ideally suited to interfacing with life sciences, since they are on the scale lengths as cells (microns) and biomacromolecules (nanometers). In this paper, we review the state of the art in bionanotechnology and bioMEMS (collectively BNM), including developments and challenges in the areas of BNM, such as microfluidic organ-on-chip devices, oral drug delivery, emerging technologies for managing infectious diseases, 3D printed microfluidic devices, AC electrokinetics, flexible MEMS devices, implantable microdevices, paper-based microfluidic platforms for cellular analysis, and wearable sensors for point-of-care testing.
UR - http://www.scopus.com/inward/record.url?scp=85176109894&partnerID=8YFLogxK
U2 - 10.1039/d3lc00296a
DO - 10.1039/d3lc00296a
M3 - Review article
C2 - 37916434
AN - SCOPUS:85176109894
SN - 1473-0197
VL - 23
SP - 4928
EP - 4949
JO - Lab on a Chip
JF - Lab on a Chip
IS - 23
ER -