Automating the processing of cDNA microarray images

P. Liatsis, M. A. Nazarboland, J. Y. Goulermas, X. J. Zeng, E. Milonidis

Research output: Contribution to journalArticlepeer-review


This work is concerned with the development of an automatic image processing tool for DNA microarray images. This paper proposes, implements and tests a new tool for cDNA image analysis. The DNAs are imaged as thousands of circularly shaped objects (spots) on the microarray image and the purpose of this tool is to correctly address their location, segment the pixels belonging to spots and extract the quality features of each spot. Techniques used for addressing, segmentation and feature extraction of spots are described in detail. The results obtained with the proposed tool are systematically compared with conventional cDNA microarray analysis software tools.

Original languageBritish English
Pages (from-to)115-144
Number of pages30
JournalInternational Journal of Intelligent Systems Technologies and Applications
Issue number1-2
StatePublished - 2008


  • addressing
  • cDNA microarrays
  • feature extraction
  • gene expression levels
  • segmentation
  • spot detection


Dive into the research topics of 'Automating the processing of cDNA microarray images'. Together they form a unique fingerprint.

Cite this