Attomole (amol) myoglobin Raman detection from plasmonic nanostructures

G. Das, F. Mecarini, F. De Angelis, M. Prasciolu, C. Liberale, Maddalena Patrini, E. Di Fabrizio

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


We have demonstrated the fabrication of nano-structures using electro-plating and electron beam lithography techniques to obtain a pattern of gold nanograin aggregate structures of diameter in the range between 80 and 100 nm with interstitial gap of 10-30 nm. The nanostructure based SERS substrate enables one to have better control and reproducibility on generation of plasmon polaritons. Using calculation, we have shown that Raman spectra are derived for the myoglobin concentration down up to attomole. These results are obtained using drop coating deposition Raman (DCDR) method in which solution of interest is microdeposited (2 μL) on SERS substrate.

Original languageBritish English
Pages (from-to)1282-1285
Number of pages4
JournalMicroelectronic Engineering
Issue number5-6
StatePublished - May 2008


  • Myoglobin
  • Surface plasmon
  • Surface-enhanced Raman scattering (SERS)


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