Asymmetric organocatalytic Michael addition of azlactones to cis-1,2-bis(phenylsulfonyl)ethene. A simple entry to quaternary α-amino acids

Natalia Bravo; Andrea Nekane R. Alba; Guillem Valero; Xavier Companyó; Albert Moyano; Ramon Rios

doi:10.1039/c0nj00321b

Asymmetric organocatalytic Michael addition of azlactones to cis-1,2-bis(phenylsulfonyl)ethene. A simple entry to quaternary α-amino acids

Natalia Bravo
, Andrea Nekane R. Alba
, Guillem Valero
, Xavier Companyó
, Albert Moyano
, Ramon Rios

Chemistry

Universitat de Barcelona

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Azlactones react with 1,2-bis(phenylsulfonyl)ethene under catalysis by simple chiral thioureas, affording α,α-disubstituted α-amino acid derivatives in good yields and in moderate to good enantioselectivities.

Original language	British English
Pages (from-to)	1816-1820
Number of pages	5
Journal	New Journal of Chemistry
Volume	34
Issue number	9
DOIs	https://doi.org/10.1039/c0nj00321b
State	Published - Sep 2010

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title = "Asymmetric organocatalytic Michael addition of azlactones to cis-1,2-bis(phenylsulfonyl)ethene. A simple entry to quaternary α-amino acids",

abstract = "Azlactones react with 1,2-bis(phenylsulfonyl)ethene under catalysis by simple chiral thioureas, affording α,α-disubstituted α-amino acid derivatives in good yields and in moderate to good enantioselectivities.",

author = "Natalia Bravo and Alba, \{Andrea Nekane R.\} and Guillem Valero and Xavier Company{\'o} and Albert Moyano and Ramon Rios",

year = "2010",

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doi = "10.1039/c0nj00321b",

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volume = "34",

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journal = "New Journal of Chemistry",

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T1 - Asymmetric organocatalytic Michael addition of azlactones to cis-1,2-bis(phenylsulfonyl)ethene. A simple entry to quaternary α-amino acids

AU - Bravo, Natalia

AU - Alba, Andrea Nekane R.

AU - Valero, Guillem

AU - Companyó, Xavier

AU - Moyano, Albert

AU - Rios, Ramon

PY - 2010/9

Y1 - 2010/9

N2 - Azlactones react with 1,2-bis(phenylsulfonyl)ethene under catalysis by simple chiral thioureas, affording α,α-disubstituted α-amino acid derivatives in good yields and in moderate to good enantioselectivities.

AB - Azlactones react with 1,2-bis(phenylsulfonyl)ethene under catalysis by simple chiral thioureas, affording α,α-disubstituted α-amino acid derivatives in good yields and in moderate to good enantioselectivities.

UR - https://www.scopus.com/pages/publications/77956135683

U2 - 10.1039/c0nj00321b

DO - 10.1039/c0nj00321b

M3 - Article

AN - SCOPUS:77956135683

SN - 1144-0546

VL - 34

SP - 1816

EP - 1820

JO - New Journal of Chemistry

JF - New Journal of Chemistry

IS - 9

ER -

Asymmetric organocatalytic Michael addition of azlactones to cis-1,2-bis(phenylsulfonyl)ethene. A simple entry to quaternary α-amino acids

Abstract

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