Asymmetric organocatalytic Michael addition of azlactones to cis-1,2-bis(phenylsulfonyl)ethene. A simple entry to quaternary α-amino acids

Natalia Bravo, Andrea Nekane R. Alba, Guillem Valero, Xavier Companyó, Albert Moyano, Ramon Rios

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Azlactones react with 1,2-bis(phenylsulfonyl)ethene under catalysis by simple chiral thioureas, affording α,α-disubstituted α-amino acid derivatives in good yields and in moderate to good enantioselectivities.

Original languageBritish English
Pages (from-to)1816-1820
Number of pages5
JournalNew Journal of Chemistry
Volume34
Issue number9
DOIs
StatePublished - Sep 2010

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