Asymmetric amplification in the amino acid-catalyzed synthesis of amino acid derivatives

Ismail Ibrahem, Henrik Sundén, Pawel Dziedzic, Ramon Rios, Armando Córdova

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The origins of biological homochirality have intrigued researchers since Pasteur's discovery of the optical activity of biomolecules. Herein, we present the first example of asymmetric amplification in the amino acid-catalyzed enantioselective synthesis of amino acid derivatives that provides support for a synergistic model for the evolution of homochirality by amino acid catalysis.

Original languageBritish English
Pages (from-to)1868-1872
Number of pages5
JournalAdvanced Synthesis and Catalysis
Volume349
Issue number11-12
DOIs
StatePublished - Aug 2007

Keywords

  • Amino acids
  • Asymmetric amplification
  • Homochirality
  • Kinetic resolution

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