Analysis for steroid production of a Sertoli-Leydig cell tumor

Ricardo Sainz De La Cuesta; John A. Rock; Riad Homsi; Daniel A. Symonds; Ira R. Horowitz

doi:10.1006/gyno.1994.1046

Analysis for steroid production of a Sertoli-Leydig cell tumor

Ricardo Sainz De La Cuesta, John A. Rock, Riad Homsi, Daniel A. Symonds, Ira R. Horowitz

College of Medicine and Health Sciences

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Sex cord stromal tumors of the ovary can be characterized by the production of virilizing steroid hormones. The authors present a case of poorly differentiated Sertoli-Leydig cell tumor in which ascitic fluid was found to have a high concentration of androgenic hormones and precursors from the delta steroid pathway (17-OH progesterone, testosterone, and androstenedione). These values correlated with samples taken from the right ovarian vein, draining the ovarian neoplasm, but not with those taken from the left ovarian vein or the peripheral blood sample. Selective peritoneal fluid sampling may aid in the diagnosis of hormonally active tumors.

Original language	British English
Pages (from-to)	276-280
Number of pages	5
Journal	Gynecologic Oncology
Volume	52
Issue number	2
DOIs	https://doi.org/10.1006/gyno.1994.1046
State	Published - Feb 1994

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title = "Analysis for steroid production of a Sertoli-Leydig cell tumor",

abstract = "Sex cord stromal tumors of the ovary can be characterized by the production of virilizing steroid hormones. The authors present a case of poorly differentiated Sertoli-Leydig cell tumor in which ascitic fluid was found to have a high concentration of androgenic hormones and precursors from the delta steroid pathway (17-OH progesterone, testosterone, and androstenedione). These values correlated with samples taken from the right ovarian vein, draining the ovarian neoplasm, but not with those taken from the left ovarian vein or the peripheral blood sample. Selective peritoneal fluid sampling may aid in the diagnosis of hormonally active tumors.",

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year = "1994",

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AU - De La Cuesta, Ricardo Sainz

AU - Rock, John A.

AU - Homsi, Riad

AU - Symonds, Daniel A.

AU - Horowitz, Ira R.

PY - 1994/2

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AB - Sex cord stromal tumors of the ovary can be characterized by the production of virilizing steroid hormones. The authors present a case of poorly differentiated Sertoli-Leydig cell tumor in which ascitic fluid was found to have a high concentration of androgenic hormones and precursors from the delta steroid pathway (17-OH progesterone, testosterone, and androstenedione). These values correlated with samples taken from the right ovarian vein, draining the ovarian neoplasm, but not with those taken from the left ovarian vein or the peripheral blood sample. Selective peritoneal fluid sampling may aid in the diagnosis of hormonally active tumors.

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Analysis for steroid production of a Sertoli-Leydig cell tumor

Abstract

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