TY - JOUR
T1 - Advances in Chlorella microalgae for sustainable wastewater treatment and bioproduction
AU - Abuhasheesh, Yazan Hani
AU - Ghazal, Aya
AU - Ying, Doris
AU - Banat, Fawzi
AU - Hasan, Shadi W.
AU - Show, Pau Loke
N1 - Publisher Copyright:
© 2025
PY - 2025/5
Y1 - 2025/5
N2 - The rising demand for effective and sustainable wastewater treatment strategies initiated a growing interest in treating wastewater with microalgal-based processes, especially Chlorella microalgae. Phycoremediation has been confirmed to be a highly effective method to efficiently remove numerous pollutants from wastewater, including industrial, municipal, household, and agricultural wastewater. This review discusses the dual role of Chlorella in both wastewater treatment and bioproduction, focusing on recent studies between 2019 and 2024. It emphasizes the ability of its different species to efficiently remediate various pollutants and the conversion of their biomass into a variety of valuable products, contributing to the circular bioeconomy. Furthermore, this review highlights the crucial role of incorporating artificial intelligence (AI) in optimizing various conditions and parameters to enhance the phycoremediation and production processes to achieve greater cost-effectiveness. Ongoing research efforts aim to improve microalgae properties through synthetic biology, link them with other microorganisms, and incorporate cutting-edge technologies. These initiatives seek to accelerate the commercialization of microalgae for wastewater bioremediation and bioproduction, thereby contributing to a more sustainable future.
AB - The rising demand for effective and sustainable wastewater treatment strategies initiated a growing interest in treating wastewater with microalgal-based processes, especially Chlorella microalgae. Phycoremediation has been confirmed to be a highly effective method to efficiently remove numerous pollutants from wastewater, including industrial, municipal, household, and agricultural wastewater. This review discusses the dual role of Chlorella in both wastewater treatment and bioproduction, focusing on recent studies between 2019 and 2024. It emphasizes the ability of its different species to efficiently remediate various pollutants and the conversion of their biomass into a variety of valuable products, contributing to the circular bioeconomy. Furthermore, this review highlights the crucial role of incorporating artificial intelligence (AI) in optimizing various conditions and parameters to enhance the phycoremediation and production processes to achieve greater cost-effectiveness. Ongoing research efforts aim to improve microalgae properties through synthetic biology, link them with other microorganisms, and incorporate cutting-edge technologies. These initiatives seek to accelerate the commercialization of microalgae for wastewater bioremediation and bioproduction, thereby contributing to a more sustainable future.
KW - Artificial intelligence
KW - Biorefinery
KW - Chlorella microalgae
KW - Circular bioeconomy
KW - Wastewater phycoremediation
UR - https://www.scopus.com/pages/publications/85218880953
U2 - 10.1016/j.ceja.2025.100715
DO - 10.1016/j.ceja.2025.100715
M3 - Review article
AN - SCOPUS:85218880953
SN - 2666-8211
VL - 22
JO - Chemical Engineering Journal Advances
JF - Chemical Engineering Journal Advances
M1 - 100715
ER -
