Abstract
Stereocontrolled formation of carbon-carbon and carbon-heteroatom bonds through asymmetric organocatalysis is a formidable challenge for modern synthetic chemistry. Among the most significant contributions to this field are the transformations involving the use of acetaldehyde or α-heteroatom-substituted acetaldehydes for constructing valuable synthons (e.g., amino acid derivatives and hydroxycarbonyl). In this Minireview, versatile (enantioselective) organocatalytic transformations are discussed.
| Original language | British English |
|---|---|
| Pages (from-to) | 2214-2234 |
| Number of pages | 21 |
| Journal | Chemistry - A European Journal |
| Volume | 22 |
| Issue number | 7 |
| DOIs | |
| State | Published - 12 Feb 2016 |
Keywords
- acetaldehyde
- aldols
- carbenes
- Mannich
- Michael
- organocatalysis