AC electrical field for the isolation of cancer cells

Waqas Waheed; Anas Alazzam; Eiyad Abu-Nada; Amjad Gawanmeh; Mohammad Al-Khaleel

doi:10.1109/IACS.2018.8355471

AC electrical field for the isolation of cancer cells

Waqas Waheed
, Anas Alazzam
, Eiyad Abu-Nada
, Amjad Gawanmeh
, Mohammad Al-Khaleel

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

A novel microdevice for the continuous separation of cancer cells from blood is presented. The device is made from two parts, glass substrate where an array of electrodes is deposited and a PDMS layer that includes a microchannel. The microsystem uses non-uniform electric field to control the movement of living cells inside a microchannel that has one inlet and two outlets. MDA-MB-231 breast cancer cells are successfully separated to a different sub-channel down the stream using non-uniform electric field generated by the layer of electrodes deposited at the bottom side of the microchannel. Numerical and experimental results for the separation of cells are presented.

Original language	British English
Title of host publication	2018 9th International Conference on Information and Communication Systems, ICICS 2018
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	223-226
Number of pages	4
ISBN (Electronic)	9781538643662
DOIs	https://doi.org/10.1109/IACS.2018.8355471
State	Published - 4 May 2018
Event	9th International Conference on Information and Communication Systems, ICICS 2018 - Irbid, Jordan Duration: 3 Apr 2018 → 5 Apr 2018

Publication series

Name	2018 9th International Conference on Information and Communication Systems, ICICS 2018
Volume	2018-January

Conference

Conference	9th International Conference on Information and Communication Systems, ICICS 2018
Country/Territory	Jordan
City	Irbid
Period	3/04/18 → 5/04/18

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

cell separation
DEP
Dielectrophoresis
electrical field for separation
microfluidics

Access to Document

10.1109/IACS.2018.8355471

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Waheed, W., Alazzam, A., Abu-Nada, E., Gawanmeh, A., & Al-Khaleel, M. (2018). AC electrical field for the isolation of cancer cells. In 2018 9th International Conference on Information and Communication Systems, ICICS 2018 (pp. 223-226). (2018 9th International Conference on Information and Communication Systems, ICICS 2018; Vol. 2018-January). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IACS.2018.8355471

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abstract = "A novel microdevice for the continuous separation of cancer cells from blood is presented. The device is made from two parts, glass substrate where an array of electrodes is deposited and a PDMS layer that includes a microchannel. The microsystem uses non-uniform electric field to control the movement of living cells inside a microchannel that has one inlet and two outlets. MDA-MB-231 breast cancer cells are successfully separated to a different sub-channel down the stream using non-uniform electric field generated by the layer of electrodes deposited at the bottom side of the microchannel. Numerical and experimental results for the separation of cells are presented.",

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author = "Waqas Waheed and Anas Alazzam and Eiyad Abu-Nada and Amjad Gawanmeh and Mohammad Al-Khaleel",

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Waheed, W, Alazzam, A , Abu-Nada, E, Gawanmeh, A & Al-Khaleel, M 2018, AC electrical field for the isolation of cancer cells. in 2018 9th International Conference on Information and Communication Systems, ICICS 2018. 2018 9th International Conference on Information and Communication Systems, ICICS 2018, vol. 2018-January, Institute of Electrical and Electronics Engineers Inc., pp. 223-226, 9th International Conference on Information and Communication Systems, ICICS 2018, Irbid, Jordan, 3/04/18. https://doi.org/10.1109/IACS.2018.8355471

AC electrical field for the isolation of cancer cells. / Waheed, Waqas; Alazzam, Anas ; Abu-Nada, Eiyad et al.
2018 9th International Conference on Information and Communication Systems, ICICS 2018. Institute of Electrical and Electronics Engineers Inc., 2018. p. 223-226 (2018 9th International Conference on Information and Communication Systems, ICICS 2018; Vol. 2018-January).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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N1 - Funding Information: The authors acknowledge the funding from Al Jalila Foundation, Dubai, UAE for this work through their seed funding program, grant # AJF201618 Publisher Copyright: © 2018 IEEE.

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AB - A novel microdevice for the continuous separation of cancer cells from blood is presented. The device is made from two parts, glass substrate where an array of electrodes is deposited and a PDMS layer that includes a microchannel. The microsystem uses non-uniform electric field to control the movement of living cells inside a microchannel that has one inlet and two outlets. MDA-MB-231 breast cancer cells are successfully separated to a different sub-channel down the stream using non-uniform electric field generated by the layer of electrodes deposited at the bottom side of the microchannel. Numerical and experimental results for the separation of cells are presented.

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KW - Dielectrophoresis

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Waheed W, Alazzam A , Abu-Nada E, Gawanmeh A, Al-Khaleel M. AC electrical field for the isolation of cancer cells. In 2018 9th International Conference on Information and Communication Systems, ICICS 2018. Institute of Electrical and Electronics Engineers Inc. 2018. p. 223-226. (2018 9th International Conference on Information and Communication Systems, ICICS 2018). doi: 10.1109/IACS.2018.8355471

AC electrical field for the isolation of cancer cells

Abstract

Publication series

Conference

UN SDGs

Keywords

Access to Document

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