AC electrical field for the isolation of cancer cells

Waqas Waheed, Anas Alazzam, Eiyad Abu-Nada, Amjad Gawanmeh, Mohammad Al-Khaleel

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

A novel microdevice for the continuous separation of cancer cells from blood is presented. The device is made from two parts, glass substrate where an array of electrodes is deposited and a PDMS layer that includes a microchannel. The microsystem uses non-uniform electric field to control the movement of living cells inside a microchannel that has one inlet and two outlets. MDA-MB-231 breast cancer cells are successfully separated to a different sub-channel down the stream using non-uniform electric field generated by the layer of electrodes deposited at the bottom side of the microchannel. Numerical and experimental results for the separation of cells are presented.

Original languageBritish English
Title of host publication2018 9th International Conference on Information and Communication Systems, ICICS 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages223-226
Number of pages4
ISBN (Electronic)9781538643662
DOIs
StatePublished - 4 May 2018
Event9th International Conference on Information and Communication Systems, ICICS 2018 - Irbid, Jordan
Duration: 3 Apr 20185 Apr 2018

Publication series

Name2018 9th International Conference on Information and Communication Systems, ICICS 2018
Volume2018-January

Conference

Conference9th International Conference on Information and Communication Systems, ICICS 2018
Country/TerritoryJordan
CityIrbid
Period3/04/185/04/18

Keywords

  • cell separation
  • DEP
  • Dielectrophoresis
  • electrical field for separation
  • microfluidics

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