A thermomechanical framework for reconciling the effects of ultraviolet radiation exposure time and wavelength on connective tissue elasticity

K. L. Goh, S. Y. Chen, K. Liao

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Augmentation of the mechanical properties of connective tissue using ultraviolet (UV) radiation—by targeting collagen cross-linking in the tissue at predetermined UV exposure time (Formula presented)$$(t)$$ (/Formula presented) and wavelength (Formula presented)$$(\lambda )$$ λ(/Formula presented)—has been proposed as a therapeutic method for supporting the treatment for structural-related injuries and pathologies. However, the effects of (Formula presented)$$\lambda $$ λ(/Formula presented) and (Formula presented)$$t$$ t(/Formula presented) on the tissue elasticity, namely elastic modulus for directing tissue stiffness and resilience. From a practical perspective, the study is a step in the direction to establish a UV irradiation treatment protocol for effective control of exogenous cross-linking in connective tissues.

Original languageBritish English
Pages (from-to)1025-1040
Number of pages16
JournalBiomechanics and Modeling in Mechanobiology
Volume13
Issue number5
DOIs
StatePublished - Oct 2014

Keywords

  • Cross-linking
  • Elastic modulus
  • Energy transfer
  • Modulus of resilience
  • Scission

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