A simple and concise catalytic asymmetric entry to tetrahydroxanthenones

Ramon Rios, Henrik Sundén, Ismail Ibrahem, Armando Córdova

Research output: Contribution to journalArticlepeer-review

55 Scopus citations

Abstract

The first catalytic asymmetric synthesis of tetrahydroxanthenones is presented. The simple organocatalytic enantioselective domino reactions between salicylic aldehyde derivatives and α,β-unsaturated cyclic ketones proceed with excellent chemoselectivity to give the corresponding tetrahydroxanthenones in moderate to good yields and high enantioselectivities.

Original languageBritish English
Pages (from-to)2181-2184
Number of pages4
JournalTetrahedron Letters
Volume48
Issue number12
DOIs
StatePublished - 19 Mar 2007

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