A one-pot organocatalytic asymmetric entry to tetrahydrothioxanthenones

Ramon Rios; Henrik Sundén; Ismail Ibrahem; Gui Ling Zhao; Armando Córdova

doi:10.1016/j.tetlet.2006.10.028

A one-pot organocatalytic asymmetric entry to tetrahydrothioxanthenones

Ramon Rios
, Henrik Sundén
, Ismail Ibrahem
, Gui Ling Zhao
, Armando Córdova

Chemistry

Arrhenius Laboratory

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

Abstract

A simple catalytic asymmetric synthesis of tetrahydrothioxanthenones is presented. The organocatalytic enantioselective domino reactions between 2-mercaptobenzaldehyde and α,β-unsaturated cyclic ketones proceed with excellent chemoselectivity to give the corresponding tetrahydrothioxanthenones in high yields and moderate to good enantioselectivities.

Original language	British English
Pages (from-to)	8679-8682
Number of pages	4
Journal	Tetrahedron Letters
Volume	47
Issue number	49
DOIs	https://doi.org/10.1016/j.tetlet.2006.10.028
State	Published - 4 Dec 2006

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title = "A one-pot organocatalytic asymmetric entry to tetrahydrothioxanthenones",

abstract = "A simple catalytic asymmetric synthesis of tetrahydrothioxanthenones is presented. The organocatalytic enantioselective domino reactions between 2-mercaptobenzaldehyde and α,β-unsaturated cyclic ketones proceed with excellent chemoselectivity to give the corresponding tetrahydrothioxanthenones in high yields and moderate to good enantioselectivities.",

author = "Ramon Rios and Henrik Sund{\'e}n and Ismail Ibrahem and Zhao, \{Gui Ling\} and Armando C{\'o}rdova",

note = "Funding Information: We gratefully acknowledge the Swedish National Research Council and Carl-Trygger Foundation for financial support.",

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T1 - A one-pot organocatalytic asymmetric entry to tetrahydrothioxanthenones

AU - Rios, Ramon

AU - Sundén, Henrik

AU - Ibrahem, Ismail

AU - Zhao, Gui Ling

AU - Córdova, Armando

N1 - Funding Information: We gratefully acknowledge the Swedish National Research Council and Carl-Trygger Foundation for financial support.

PY - 2006/12/4

Y1 - 2006/12/4

N2 - A simple catalytic asymmetric synthesis of tetrahydrothioxanthenones is presented. The organocatalytic enantioselective domino reactions between 2-mercaptobenzaldehyde and α,β-unsaturated cyclic ketones proceed with excellent chemoselectivity to give the corresponding tetrahydrothioxanthenones in high yields and moderate to good enantioselectivities.

AB - A simple catalytic asymmetric synthesis of tetrahydrothioxanthenones is presented. The organocatalytic enantioselective domino reactions between 2-mercaptobenzaldehyde and α,β-unsaturated cyclic ketones proceed with excellent chemoselectivity to give the corresponding tetrahydrothioxanthenones in high yields and moderate to good enantioselectivities.

UR - https://www.scopus.com/pages/publications/33750471190

U2 - 10.1016/j.tetlet.2006.10.028

DO - 10.1016/j.tetlet.2006.10.028

M3 - Article

AN - SCOPUS:33750471190

SN - 0040-4039

VL - 47

SP - 8679

EP - 8682

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

ER -

A one-pot organocatalytic asymmetric entry to tetrahydrothioxanthenones

Abstract

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