TY - JOUR
T1 - A comparison of danazol and conservative surgery for the treatment of infertility due to mild or moderate endometriosis
AU - Guzick, D. S.
AU - Rock, J. A.
N1 - Funding Information:
Received March 17, 1983; revised and accepted June 29, 1983. *Supported in part by a grant from Winthrop Laboratories, New York, New York. tPresented at the Thirty-Ninth Annual Meeting of The American Fertility Society, April 16 to 20, 1983, San Francisco, California. tReprint requests: John A. Rock, M.D., Director, Department of Gynecology and Obstetrics, Halsted 124, The Johns Hopkins Hospital, Baltimore, Maryland 21205.
PY - 1983
Y1 - 1983
N2 - Although both medical and surgical therapy have been widely used in the treatment of infertility due to endometriosis, there is little information on the comparative success of these treatment modalities. In a group of 313 infertile women who presented to the Johns Hopkins Hospital with mild or moderate endometriosis in whom there had been no previous therapy, the results of danazol (91 patients) and conservative surgery (133 patients) were compared. It was found that the cumulative pregnancy curves of the two groups virtually coincided. There was no significant difference in the estimated proportion of patients who were 'cured' i.e., who would ultimately conceive if followed for a long enough period (68.3% for surgery versus 74.0% for danazol), nor in the monthly rate of pregnancy among those cured (5.7% versus 4.0%), respectively.
AB - Although both medical and surgical therapy have been widely used in the treatment of infertility due to endometriosis, there is little information on the comparative success of these treatment modalities. In a group of 313 infertile women who presented to the Johns Hopkins Hospital with mild or moderate endometriosis in whom there had been no previous therapy, the results of danazol (91 patients) and conservative surgery (133 patients) were compared. It was found that the cumulative pregnancy curves of the two groups virtually coincided. There was no significant difference in the estimated proportion of patients who were 'cured' i.e., who would ultimately conceive if followed for a long enough period (68.3% for surgery versus 74.0% for danazol), nor in the monthly rate of pregnancy among those cured (5.7% versus 4.0%), respectively.
UR - http://www.scopus.com/inward/record.url?scp=0021077399&partnerID=8YFLogxK
U2 - 10.1016/s0015-0282(16)47412-1
DO - 10.1016/s0015-0282(16)47412-1
M3 - Article
C2 - 6628703
AN - SCOPUS:0021077399
SN - 0015-0282
VL - 40
SP - 580
EP - 584
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 5
ER -