A bionic sphincter for stress urinary incontinence: Design and preliminary experiments

Kenana Al Adem, Sarah S. Bawazir, Khulood Alameri, Gioia Lucarini, Tommaso Mazzocchi, Cesare Stefanini, Paolo Dario, Arianna Menciassi

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The treatment of severe Stress urinary incontinence (SUI) SUI cases requires the implantation of an artificial urinary sphincter (AUS). The current gold standard AUS presents a number of well-reported complications, including: mechanical breakdown, urethral atrophy, and cuff erosion. Patients implanted with AUS have a difficult lifestyle with 60% requiring re-visitation and re-operation [1]. The work reported in this paper provides a promising solution for a smart artificial sphincter that minimizes urethral atrophy through automatic re-adjustment of the pressure applied on the bulbous urethra to provide continence dynamically controls the occlusion of the urethral cuff. The effectiveness of artificial urinary sphincters device in maintaining continence was tested on an in vitro set-up replicating the different parts of the urinary system. The final in vitro test bed consisted of a prototyped silicone bladder, a urethra and a ureter from the same material, along with a support system that houses these components for experimental characterization. The choice of silicone as the material for the phantoms used in the set-up was done after producing several models made from various polymers. It was found that the models made of a specific silicone with Shore hardness 2A were closer in terms of mimicking the mechanical characteristics of the muscles in the parts of interest. The contribution of this work is in providing an in vitro test bed that can be used by researchers to test the AUS systems they develop, by surgeons to practice implantation and by physicians to explain the surgical treatment to their patients. The test bed also represents an option to avoid animal experiments in preliminary testing.

Original languageBritish English
Title of host publicationIntelligent Human Systems Integration - Proceedings of the 1st International Conference on Intelligent Human Systems Integration IHSI 2018
Subtitle of host publicationIntegrating People and Intelligent Systems
EditorsWaldemar Karwowski, Tareq Ahram
PublisherSpringer Verlag
Pages203-208
Number of pages6
ISBN (Print)9783319738871
DOIs
StatePublished - 2018
Event1st International Conference on Intelligent Human Systems Integration: Integrating People and Intelligent Systems, IHSI 2018 - Dubai, United Arab Emirates
Duration: 7 Jan 20189 Jan 2018

Publication series

NameAdvances in Intelligent Systems and Computing
Volume722
ISSN (Print)2194-5357

Conference

Conference1st International Conference on Intelligent Human Systems Integration: Integrating People and Intelligent Systems, IHSI 2018
Country/TerritoryUnited Arab Emirates
CityDubai
Period7/01/189/01/18

Keywords

  • Artificial urinary sphincters (AUS)
  • Cuff erosion
  • In vitro
  • Invasive surgery
  • Urinary system phantom

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