TY - JOUR
T1 - 3D and 4D Bioprinting Technologies
T2 - A Game Changer for the Biomedical Sector?
AU - Noroozi, Reza
AU - Arif, Zia Ullah
AU - Taghvaei, Hadi
AU - Khalid, Muhammad Yasir
AU - Sahbafar, Hossein
AU - Hadi, Amin
AU - Sadeghianmaryan, Ali
AU - Chen, Xiongbiao
N1 - Publisher Copyright:
© 2023, The Author(s) under exclusive licence to Biomedical Engineering Society.
PY - 2023/8
Y1 - 2023/8
N2 - Bioprinting is an innovative and emerging technology of additive manufacturing (AM) and has revolutionized the biomedical sector by printing three-dimensional (3D) cell-laden constructs in a precise and controlled manner for numerous clinical applications. This approach uses biomaterials and varying types of cells to print constructs for tissue regeneration, e.g., cardiac, bone, corneal, cartilage, neural, and skin. Furthermore, bioprinting technology helps to develop drug delivery and wound healing systems, bio-actuators, bio-robotics, and bio-sensors. More recently, the development of four-dimensional (4D) bioprinting technology and stimuli-responsive materials has transformed the biomedical sector with numerous innovations and revolutions. This issue also leads to the exponential growth of the bioprinting market, with a value over billions of dollars. The present study reviews the concepts and developments of 3D and 4D bioprinting technologies, surveys the applications of these technologies in the biomedical sector, and discusses their potential research topics for future works. It is also urged that collaborative and valiant efforts from clinicians, engineers, scientists, and regulatory bodies are needed for translating this technology into the biomedical, pharmaceutical, and healthcare systems.
AB - Bioprinting is an innovative and emerging technology of additive manufacturing (AM) and has revolutionized the biomedical sector by printing three-dimensional (3D) cell-laden constructs in a precise and controlled manner for numerous clinical applications. This approach uses biomaterials and varying types of cells to print constructs for tissue regeneration, e.g., cardiac, bone, corneal, cartilage, neural, and skin. Furthermore, bioprinting technology helps to develop drug delivery and wound healing systems, bio-actuators, bio-robotics, and bio-sensors. More recently, the development of four-dimensional (4D) bioprinting technology and stimuli-responsive materials has transformed the biomedical sector with numerous innovations and revolutions. This issue also leads to the exponential growth of the bioprinting market, with a value over billions of dollars. The present study reviews the concepts and developments of 3D and 4D bioprinting technologies, surveys the applications of these technologies in the biomedical sector, and discusses their potential research topics for future works. It is also urged that collaborative and valiant efforts from clinicians, engineers, scientists, and regulatory bodies are needed for translating this technology into the biomedical, pharmaceutical, and healthcare systems.
KW - 3D bioprinting
KW - 4D bioprinting
KW - Additive manufacturing
KW - Biomedical applications
KW - Tissue engineering
UR - http://www.scopus.com/inward/record.url?scp=85160852339&partnerID=8YFLogxK
U2 - 10.1007/s10439-023-03243-9
DO - 10.1007/s10439-023-03243-9
M3 - Review article
C2 - 37261588
AN - SCOPUS:85160852339
SN - 0090-6964
VL - 51
SP - 1683
EP - 1712
JO - Annals of Biomedical Engineering
JF - Annals of Biomedical Engineering
IS - 8
ER -