Triple Quadrupole Mass Spectrometry (LCMS)

The Waters UPLC H-Class PLUS system is an ultra-performance liquid chromatography (UPLC) system designed by Waters Corporation. UPLC is an advanced form of HPLC that uses smaller particle sizes and higher pressure to achieve faster, more efficient separations with better resolution. When paired with a triple quadrupole mass spectrometer, the combination offers highly sensitive and selective quantitative analyses. A triple quadrupole mass spectrometer offers ultra-high sensitivity and selectivity. It's often used for targeted quantitative analyses due to its ability to filter specific ions and eliminate background noise. The triple quadrupole setup allows for MRM (Multiple Reaction Monitoring) mode, which enhances its quantitative capabilities. Such a system is incredibly versatile and is frequently utilized in pharmaceuticals for drug development and quality control, in environmental labs for trace analysis of contaminants, and in clinical research for biomarker studies.