This course provides a comprehensive overview of the technical, economic, and policy dimensions of nuclear power generation in the context of achieving net-zero emissions. Students gain an understanding of nuclear technology fundamentals, the fuel cycle, and the integration of nuclear energy with renewables. The course is not limited to electricity production; it includes nuclear applications like desalination, hydrogen production, space use, and ship propulsion. It examines advancements in reactor designs and the utilization of emerging technologies such as AI and 3D printing.